Monotherapy with P2Y12-inhibitors after dual antiplatelet therapy: Filling gaps in evidence

pubmed

Int J Cardiol. 2024 Feb 19:131893. doi: 10.1016/j.ijcard.2024.131893. Online ahead of print. ABSTRACT BACKGROUND: Whether P2Y12 inhibitor monotherapy (P2Y12-I) is superior to aspirin following DAPT discontinuation post-PCI remains to be established. METHODS: We updated our prior network meta-analysis where P2Y12-I and aspirin had been compared with DAPT or directly with each other. The focus is…

Non-compliance treatment in a young adult full-step class II division 2 malocclusion with preadjusted lingual appliance and upper first molars extractions

pubmed

Int Orthod. 2024 Feb 19;22(2):100848. doi: 10.1016/j.ortho.2024.100848. Online ahead of print. ABSTRACT This case report describes a complex full-step class II case in a young adult patient treated with lingual straight-wire appliance and upper first molar extraction. As the patient refused a surgical treatment, she was offered the best possible camouflage with the double aim…